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Home BPharma Physics Pharmaceutics I To prepare the 10 ml of piperazine citrate elixir
Physics Pharmaceutics I Lab Experiments

To prepare the 10 ml of piperazine citrate elixir



Aim

To prepare the 10 ml of piperazine citrate elixir.

Apparatus Required:

Beakers, glass rod, measuring cylinder.

Category:Anti helmintic

Formula:

S. No. Ingredients Official Formula(I.P.)
1 Piperazine citrate 18 gm
2 Chloroform spirit 0.5ml
3 Glycerin 10 ml
4 Syrup 50 ml
5 Purified water q. s. to100ml

Principle:

Elixirs are flavored hydro alcoholic solutions to which glycerin often is added to enhance the solvent properties. The alcohol which is present in the chloroform spirit act as a preservative. Piperazine citrate is unpleasant taste which is masked with the syrup to prevent the unpleasant taste of elixir.

Procedure:

Piperazine citrate is dissolved in small amount of purified water. Glycerin, syrup and chloroform spirit are mixed. Sufficient volume of water is added to produce the final volume.

Dispensing:

Transfer the elixir to a clear or amber colored, narrow mouthed glass bottle, close it thoroughly with metallic screw cap, polish and label.

Storage:

Store in a closed container at a temperature not exceeding 250C.

Direction:

4-15ml daily in divided doses to be taken at night.

Note:Anti helmintic is a type of drug or herbal preparation given to destroy the parasitic worms or expel them from the body